麻薬 could 傷をいやす/和解させる spinal 傷害s

by ANDREA PERRY, femail.co.uk

People who are 永久的に paralysed - like Superman actor Christopher Reeve - may one day be able to take a 麻薬 which will 修理 spinal 傷害s.

Although the 研究 is still in its 幼少/幼藍期, scientists believe they have 設立する the 重要な to regenerating 損失d 神経 独房s.

The 発見 might 結局 lead to the 開発 of a 麻薬 which will enable the central nervous system to 修理 itself after 傷害.

Broken spinal cords could grow 支援する together and it may also be possible to 修理 brain 傷害s 原因(となる)d by 一打/打撃s or blows to the skull, or 停止(させる) the 破滅的な progression of 多重の sclerosis.

Neurones in the central nervous system, or CNS - the brain and spinal cord - do not regenerate after 傷害, unlike 神経s in other parts of the 団体/死体.

If the spinal cord is 厳しいd, it stays 厳しいd. That is why 犠牲者s of spinal 傷害 such as Mr Reeve, who was 傷つける in a riding 事故, are often 手足を不自由にする/(物事を)損なうd for life.

The 失敗 of CNS axons, the long 武器 of 神経 独房s, to regenerate is 大部分は 予定 to a potent growth inhibitor given the 指名する 'Nogo' by scientists.

This is produced by 独房s that sheath axons in the 絶縁するing protein myelin.

The US scientists at Yale University School of 薬/医学 at New 港/避難所, Connecticut, believe they have now 設立する the molecular 'switch' that gives Nogo the 力/強力にする to 妨げる the growth of 神経s.

It is a molecular 'lock' or 'receptor' into which Nogo fits like a 重要な. 封鎖するing the receptor with a 類似して 形態/調整d 分子 in a 麻薬 could stop Nogo latching on to it and having an 影響.

The 研究員s, led by Stephen Strittmatter, 設立する the receptor using 遺伝子s from mouse brain 独房s. One bit of デオキシリボ核酸 was 設立する that produced a 細胞の protein, which bound 堅固に to Nogo, and was identified as the Nogo receptor.

令状ing in Nature, the scientists said finding the receptor 'should 大いに 容易にする the 開発 of スパイ/執行官s with 製薬の 可能性のある in a diverse group of neurological 条件s, such as spinal cord 傷害, brain 外傷/ショック, 一打/打撃 影響する/感情ing white 事柄, and chronic, 進歩/革新的な, 多重の sclerosis.'

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