警告実験（する） for Alzheimer's

by JAMES CHAPMAN, Daily Mail

Scientists have developed an 早期に-警告実験（する） for Alzheimer's in a major 打開 in the fight against the 病気.

実験（する）ing a 見本 of spinal fluid could （悪事，秘密などを）発見する the first 調印するs of the illness years before symptoms appear, say 専門家s.

This could 許す治療 with 存在するing 麻薬s known to help slow the progression of the 病気 in some 患者s.

An 早期に-警告実験（する）代表するs the most important 前進する for years in the Alzheimer's 戦う／戦い.

The 実験の実験（する） has shown a high level of 正確 in an 初期の熟考する／考慮する, raising hopes that it could soon 申し込む／申し出 a much better way of （悪事，秘密などを）発見するing the 病気.

'If we can 診断する患者s earlier, we could 供給する them with 医薬s to help minimise their symptoms,' said Dr Odile Carrette, of Geneva University Hospital, in Switzerland, who 開拓するd the 実験（する）. People could also be told to 修正する their lifestyles. Smoking, poor diet and 欠如（する） of 演習 have all been linked to 増加するd progression of Alzheimer's.

In the 熟考する／考慮する, Dr Carrette and 同僚s carried out ' blind' 実験（する）s on spinal fluid taken from 20 volunteer 患者s. Ten had already been 診断するd with Alzheimer's, while the other ten were healthy.

Using a 実験（する）ing technique that can identify clusters of proteins in the fluid 見本s, the scientists 設立する that as many as 17 proteins appeared in either higher or lower levels in the Alzheimer's 患者s than in the others.

Two 重要な markers of the 病気 were proteins called cystatin C and beta 2 microglobulin, which the 研究員s had 以前 linked with Alzheimer's.

Based on the protein levels, 研究員s 正確に identified the illness in nine of the ten 患者s 以前診断するd with the 病気, and 支配するd it out in the other ten. The more protein markers the volunteers had, the more likely they were to have Alzheimer's, Dr Carrette told the 年次の会合 of the Fe deration for American Societies of 実験の Biology in San Diego, California.

She said it would take several years of その上の研究 before the 実験（する） could become 広範囲にわたって利用できる.

But scientists 計画（する） to see if the 重要な

proteins are also 現在の in the 血, which could lead to a more simple 実験（する）. Other 研究 scientists are working on ways to （悪事，秘密などを）発見する早期に調印するs of Alzheimer's. One 可能性 is taking ざっと目を通すs of the brain.

U.S. 研究員s 示唆する that a 重要な地域 of the brain starts to change in people who go on to develop Alzheimer's １０年間s later.

Several 医療の teams are also working on possible 血実験（する）s to 審査する for people at high 危険.

現在／一般に, the only way to definitively 診断する Alzheimer's is by 診察するing a person's brain after their death.

Doctors have to 診断する the 病気 in living 患者s おもに by 査定する／（税金などを）課すing symptoms such as memory loss and disorientation, but these can be mistaken for other forms of dementia.

Alzheimer's, which 原因（となる）s shrinkage of the brain, rarely occurs before the age of 60, but almost one in ten people over 65 is struck 負かす／撃墜する - some 700,000 people in the UK.

犠牲者s 含む小説家 Iris Murdoch, who died three years ago, and former U.S. 大統領 Ronald Reagan.

New 恐れる over link to aluminium in water

専門家s say there is new 証拠 that aluminium in drinking water could be linked to Alzheimer's.

The theory had been 大部分は割引d, but 研究示唆するs the 病気 is more ありふれた in 地域s where levels of aluminium in the water are highest.

Scientists said that when they 実験（する）d the 影響s of one form of the metal on human 独房s it 急いでd 独房 death.

研究員s in California 焦点（を合わせる） d on monomeric aluminium, which they said was most easily 吸収するd by human 独房s.

Together with scientists from Turin they 実験（する）d water in north-west Italy and 設立する aluminium levels 範囲d from five to 1,220 micrograms per litre. Recommended levels are 200 micrograms.

研究員s 設立する Alzheimer's was more ありふれた in areas with the highest levels of monomeric aluminium.