Life-saving facts all women should know about estrogens (but probably don't)

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One of every eight women in the 部隊d 明言する／公表するs will develop invasive breast 癌 over her lifetime.?

Eighty パーセント of those 癌s are 燃料d in part by estrogens.

One 治療 for women whose breast 癌 is 燃料d by estrogen ? or what is often called estrogen receptor (ER)-肯定的な breast 癌 ? is for them to take 麻薬s that 封鎖する estrogens.?

But estrogens have 利益s that should be considered.

This 特に 影響する／感情s postmenopausal women who have gone through the 外傷／ショック of 外科 for invasive breast 癌.?

One of every eight women in the 部隊d 明言する／公表するs will develop invasive breast 癌 over her lifetime. Eighty パーセント of those 癌s are 燃料d in part by estrogens

They are typically 直面するd with a very difficult 決定／判定勝ち（する）.?

Should they take estrogen blockers or not? Is the 治療 価値（がある） it, balancing the 危険 of 再発 of the 癌 with 可能性のある 質-of-life 問題／発行するs?

When 定める／命ずるing a particular 麻薬 for postmenopausal, ER-肯定的な, breast 癌 生存者s, 内科医s often consider the 影響s of estrogen blockers on bone and the uterus.

However, they also need to consider the 影響s on other 面s of these women's health.?

Estrogens also have many 肯定的な 影響s on mental health, cognitive 機能（する）／行事, libido and 保護 of the brain, かもしれない even slowing the onset of Alzheimer's 病気.

I am a neuroendocrinologist, and I have 熟考する／考慮するd the 影響s of hormones, 含むing estrogens, on the brain, 行為 and mental health for over 40 years.?

Not only is the fact that 'estrogen' is 現実に a class of hormones not 井戸／弁護士席 understood, but so are the many 肯定的な 機能（する）／行事s of estrogens. As with any health 治療, the 可能性のある 消極的な 影響s should be 重さを計るd against the 可能性のある 肯定的な 影響s.

There is no hormone called estrogen?

First, a primer on what 正確に／まさに 'estrogen' is. There is 現実に no hormone called 'estrogen.' Estrogens are a class of hormones.?

There are thre e different forms of estrogens in the 団体／死体: estradiol, estriol and estrone.?

Although they are all pretty 類似の in 機能（する）／行事, they 変化させる in potency.?Estrogens 設立する in 工場／植物s, like soy, are also いつかs 簡単に called 'estrogen,' although their 影響s may 異なる from those of the estrogens produced in the 団体／死体.

Estradiol is the 支配的な estrogen 広まる 事前の to menopause. It is produced おもに in the ovaries.?

In most 事例／患者s, this is the most potent form of estrogen. During pregnancy, the 支配的な form is estriol, produced by the placenta. And during menopause, when the levels of estradiol 減少（する）, the 支配的な estrogen is estrone, produced in fat tissue.

Doctors need to consider?the 影響s of estrogen blockers on other 面s of women's health

The ovaries stop producing estrogens during menopause, resulting in lower levels of estrogens in the 団体／死体. Yet other 組織／臓器s, 含むing fat and the brain, c ontinue to produce them.?

There are still estrogens doing whatever they were doing before, but because their levels are lower, they are not doing their work as 効果的に.

One class of estrogen blockers that is often 定める／命ずるd for women with estrogen receptor-肯定的な breast 癌 does its 職業 by 封鎖するing estrogens from getting to the receptors of the 独房s in the 団体／死体, 含むing 癌 独房s.?

The 団体／死体 still produces estrogens, but their 影響s are 封鎖するd in some 独房s.

A second class, called aromatase inhibitors, 封鎖するs the 生産／産物 of estrogens. Both types of estrogen blocker 行為／法令／行動する in the brain 同様に as the breast, ovaries, vagina and many other parts of the 団体／死体.

Since these 麻薬s 封鎖する the 影響s of estrogens, we should 推定する／予想する that, besides 封鎖するing the 消極的な 影響s of estrogens on the breast 癌, they will 封鎖する the 肯定的な 影響s on the brain and on mental health.

Unfortunately, many 実験s 直接／まっすぐに 査定する／（税金などを）課すing the 影響s of these 麻薬s in breast 癌 生存者s are 行方不明の 必須の 支配（する）／統制するs.?

It would not be 倫理的な to give one group of women with a high 危険 of 再発 of breast 癌 a placebo.

However, although much more 研究 on the 影響s of anti-estrogens in postmenopausal women with breast 癌 is needed, by considering what we know about the 影響s of estrogens from animal 熟考する／考慮するs, all that we know about the 影響s of estrogens in women without breast 癌 and what we know from some 熟考する／考慮するs about the 影響s of anti-estrogens in breast 癌 生存者s, we can 結論する that anti-estrogens are likely to 妥協 質 of life in some women.

What are the 肯定的な 影響s of estrogens??

The many 肯定的な 機能（する）／行事s of estrogens and their 影響s on health are often underestimated.

Estrogens are 責任がある the 開発 of reproductive tissues and 女性（の） 第２位 性の 特徴 (like breasts) at puberty.?

They also 持続する bone 濃度／密度 and 減少（する） the 危険 of osteoporosis, which can result in brittle bones that break easily. But the 役割 estrogens play in women's health goes far beyond reproductive health and bone 濃度／密度.

Some of the most 深遠な 影響s of estrogens are in the brain.?

For instance, hot flashes, which many women experience while going through menopause, are 予定 to the loss of estrogens 事実上の／代理 on brain areas 伴う／関わるd in 気温 規則.

They can also 影響（力） cognitive 機能（する）／行事 ? how we think, 特に 言葉の memory and fluency, which is the memory of words and how we 表明する ourselves in language. And around the time of menopause in many women, they are believed to have an anti-depressive 影響.

Sleep 騒動s during menopause are believed to be 原因（となる）d by absence of the estrogens 事実上の／代理 on sleep 中心s in the brain.?

The 減少（する）d 活動／戦闘s of estrogens on the brain during menopause may also 影響（力） 性の 願望（する）.

And finally, estrogens may be 保護の in the brain. This has been 論証するd in nonhuman 大主教s.?

In women, estrogens may 減少（する） the incidence of Alzheimer's 病気 if hormone 交替／補充 begins soon after menopause.

After menopause, the level of estrogens 減少（する）s to low 量s. Appreciable 量s are still produced in fat tissue.?

We now believe that the brain also produces some estrogens 同様に, a topic that is 存在 熟考する／考慮するd 権利 now.

重さを計るing the プロの／賛成のs and 反対／詐欺s of estrogen blockers?

Should women with estrogen receptor-肯定的な breast 癌 take inhibitors of estrogens??

The 決定／判定勝ち（する） of whether or not to use estrogen blockers is a コンビナート／複合体 one that each woman must make in 協議 with her oncologist.

The 可能性のある 消極的な 影響s of these blockers on the brain and 質 of life should be 重さを計るd against the 可能性のある 肯定的な 影響s on 再発 of the 癌.?

The answer to this will depend on the 絶対の 危険 of 再発 of the 癌.

In making a 決定／判定勝ち（する） about a 治療 that could 衝撃 質 of life, it would be most helpful to speak with an oncologist who is fully aware of the 可能性のある 消極的な, 同様に as 肯定的な, 影響s of these 麻薬s.

This article was 初めは published by The Conversation