Coleen Rooney 示すs her late sister Rosie's birthday with a 甘い ビデオ ten years after her death 老年の 14

  • Rosie passed away 老年の 14 in 2013 に引き続いて her lifelong 戦う／戦い with Rett syndrome, a rare brain disorder that 原因（となる）s 厳しい disabilities?
  • She was 初めは taken in as a foster child by Coleen's parents, bricklayer Tony and Colette, a former nursery nurse, when she was two?

By Laura Parkin For Mailonline

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Coleen Rooney 示すd her late sister Rosie's birthday with a 甘い ビデオ on Thursday, ten years after?she passed away 老年の 14.

The WAG, 36, who is married to Wayne Rooney, celebrated?what would have been her sisters 24th birthday and said 'love you.'

Rosie passed away in 2013 に引き続いて her lifelong 戦う／戦い with Rett syndrome, a rare brain disorder that 原因（となる）s 厳しい disabilities.?

In the clip 地位，任命するd to Instagram, Coleen could be seen playing with Rosie as she giggled before 工場／植物ing a kiss on her 直面する.?

と一緒に the ビデオ, she penned: 'Happy Birthday Rosie. Love you,' which was met by 深く心に感じた comments from her friends and fans.?

Tribute: Coleen Rooney, 36, marked her late sister Rosie's birthday with a sweet video on Thursday, ten years after she passed away aged 14

尊敬の印: Coleen Rooney, 36, 示すd her late sister Rosie's birthday with a 甘い ビデオ on Thursday, ten years after she passed away 老年の 14

Last month, Coleen?株d a 甘い family photo to Instagram with Rosie cuddled up in her mothers 武器 as she 示すd the tenth 周年記念日 of her death.

Coleen captioned the 地位，任命する: '10 years today……We all love and 行方不明になる you Rosie Mc', with her 信奉者s 株ing their 弔慰s in the comment section.???

Rosie bravely fought a lifelong 戦う／戦い with Rett syndrome ? a rare brain disorder that 影響する／感情s physical movement and can bring about many different symptoms in each individual 事例／患者.?

Rosie was 初めは taken in as a foster child by Coleen's parents, bricklayer Tony and Colette, a former nursery nurse, when she was two.

Although they were aware she was 無能にするd they did not know the 十分な extent of her 条件, which has no cure.

In an 排除的 article for The Mail on Sunday in 2006, Coleen wrote: 'When Rosie arrived she could はう, and even though she couldn't use her 手渡すs that much she would 扱う toys on her play mat and she could eat.

'But over a period of time she stopped はうing and lost what use of her 手渡すs she had. Then she started having problems swallowing her food.

'It took pretty much a year for Rosie to be 診断するd and, looking 支援する, I can see how much Mum 押し進めるd to find out what was wrong with her and to try to do what was best for her.'

Upsetting: Rosie passed away in 2013 following her lifelong battle with Rett syndrome, a rare brain disorder that causes severe disabilities

Upsetting: Rosie passed away in 2013 に引き続いて her lifelong 戦う／戦い with Rett syndrome, a rare brain disorder that 原因（となる）s 厳しい disabilities

Cute:?In the clip posted to Instagram, Coleen could be seen playing with Rosie as she giggled before planting a kiss on her face

削減（する）:?In the clip 地位，任命するd to Instagram, Coleen could be seen playing wi th Rosie as she giggled before 工場／植物ing a kiss on her 直面する

Coleen was said to idolise her 可決する・採択するd sister and chose Rosie as 長，指導者 bridesmaid when she married Wayne in 2008.

In a 声明 解放（する）d すぐに after her death, Tony and Colette wrote: 'Sadly our special angel Rosie, our much-loved daughter and sister, went to Heaven at 2.50 this morning at home where she was surrounded by her loving family.

'Rosie was just 14 years old and fought a lifelong 戦う／戦い with Rett syndrome. Throughout her life she brought so much love and happiness to all our family and everyone who knew and met her.'

Last month, Coleen shared a sweet family photo to Instagram with Rosie cuddled up in her mothers arms as she marked the tenth anniversary of her death

Last month, Coleen 株d a 甘い family photo to Instagram with Rosie cuddled up in her mothers 武器 as she 示すd the tenth 周年記念日 of her death

Sweet:?Rosie was originally taken in as a foster child by Coleen's parents, bricklayer Tony and Colette (pictured), a former nursery nurse, when she was two

甘い:?Rosie was 初めは taken in as a foster child by Coleen's parents, bricklayer Tony and Colette (pictured), a former nursery nurse, when she was two

'She was such a strong little girl and an inspiration to us all. We shall 心にいだく for ever the memories we have 株d and the love she showed us each and every day of her life.

The couple 結論するd: 'As a family we are heartbroken but we are blessed to have had her in our lives.'

Coleen had been on holiday in Barbados with her younger brothers, Joe and Anthony, but 削減（する） short the trip when she heard that Rosie's 条件 had 悪化するd.

WHAT IS RETT SYNDROME? THE NEUROLOGICAL DISORDER THAT LEAVES KIDS UNABLE TO SPEAK, EAT, WALK, TALK AND BREATHE

One child in 12,000 is born with Rett Syndrome, yet few people have heard of it.

The genetic disorder 影響する／感情s almost 排他的に 女性（の）s, 原因（となる）ing them to regress neurologically and 肉体的に.

The progression of the 病気 can be 概略で divided into four 行う／開催する／段階s.

During the first 行う／開催する／段階, from about the age of six to 18 months, a baby slows in 開発, loses 利益／興味 in play, stops making 注目する，もくろむ 接触する, starts walking awkwardly and makes repetitive 手渡す movements.

The second 行う／開催する／段階, known as ‘早い 破壊’, begins between the ages of one and four.

The child finds it ますます difficult to communicate and learn and there is often a 悪化／低下 in other brain 機能（する）／行事s.

Symptoms 含む an 無（不）能 to 支配（する）／統制する the 手渡すs, sudden 苦しめる teamed with 叫び声をあげるing, unsteadiness, breathing problems, difficulty sleeping, slow 長，率いる growth and digestive problems.

The third 行う／開催する／段階, the ‘高原’, begins between age three and ten.

四肢s become floppy, epilepsy may develop and there may be 負わせる loss and teeth-grinding.

However, many parents say children are いっそう少なく 苦しめるd and show more 利益／興味 in their surroundings.

The final 行う／開催する／段階 can last for １０年間s. Usually 厳しい bending of the spine ? scoliosis ? develops, 同様に as losing the ability to walk.

Almost all 事例／患者s are 原因（となる）d by a 突然変異 in the MECP2 遺伝子 which 妨げるs 神経 独房s in the brain from working 適切に.

現在／一般に there is no cure and only the symptoms are 扱う／治療するd .?

Around three ４半期/4分の1s of 苦しんでいる人s will live into their 50s, によれば Rett UK. The 国家の 学校／設ける of Health says it's not possible to make reliable 見積（る）s about life 見込み beyond the age of 40.?

によれば Rettsyndrome.org, data from the Natural History 熟考する／考慮する have 決定するd that a girl with Rett has a 100 per cent chance of reaching age 10, greater than 75 per cent chance of reaching age 30, and a greater than 50 per cent chance of reaching age 50.?

But 予定 to the rarity of Rett, very little has been published about life 見込み.?

Wayne RooneyColeen Rooney

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