ビタミン D fails to 妨げる type 2 糖尿病 in large 熟考する／考慮する
By 遺伝子 Emery
(Reuters Health) - If you're talking ビタミン D and 推定する／予想するing it to lower your 危険 of getting type 2 糖尿病 when you get older, it's time to lower your 期待s.
A new 熟考する／考慮する, the largest of its 肉親，親類d, has 設立する that taking 4000 international 部隊s (IU) per day, which is on the upper 限界 of the recommended intake, may 二塁打 the 量 of ビタミン D in the 血 but it gives most people 概略で the same chance of developing 血 sugar problems as people who don't take the ビタミン.
After about 2.5 years, 糖尿病 appeared at a 率 of 9.4% per year with ビタミン D 補足（する）s and 10.7% with placebo 要約する／（宇宙ロケットの）カプセルs, an insignificant difference. All the 患者s were already at high 危険 for developing type 2 糖尿病 and 80% already had 適する levels of the ビタミン.
For the 5% of the 全住民 "with very low levels of ビタミン D, there appears to be a 利益, but we would 勧める 警告を与える and not have people overreact to that," 長，指導者 author Dr. Anastassios Pittas told Reuters Health in a telephone interview.
Even if the ビタミン helped this group to lower their 糖尿病 危険 - and the numbers were too small to 証明する that - "these people would need to take ビタミン D anyway so it doesn't change the 推薦s," said Dr. Pittas, co-director of the 糖尿病 and Lipid 中心 at Tufts 医療の 中心 in Boston.
ビタミン D also keeps bones healthy and doctors may recommend a 補足（する） for other 推論する／理由s 同様に. Many foods 追加する the ビタミン.
The 熟考する／考慮する, 報告（する）／憶測d online by The New England 定期刊行物 of 薬／医学 and at a 会合 of the American 糖尿病 協会 in San Francisco, 伴う／関わるd 2,423 volunteers who were at high 危険 for developing the adult-onset 見解／翻訳／版 of the 病気, which can often be 妨げるd with diet and 演習.
About 29 million Americans already have type 2 糖尿病 and it is the 7th 主要な 原因（となる） of death in the U.S., によれば the American 糖尿病 協会. More than 84 mill イオン adults are at 危険 for the 病気.
Previous 研究 設立する that people with low levels of ビタミン D 直面するd a higher 危険. The new 熟考する／考慮する, known as D2d, was designed to 実験（する） whether supplementation would 削減（する） the 半端物s.
All the volunteers met two out of three 基準 for pre-糖尿病, making it more likely that ビタミン D - if 効果的な - would help them.
最終的に, 616 developed 糖尿病: 293 in the ビタミン D group and 323 who were taking placebo 要約する／（宇宙ロケットの）カプセルs. But when the 研究員s adjusted for how long the 患者s had been in the 熟考する／考慮する and other factors, they 設立する that the chances of developing type 2 糖尿病 were too 類似の to 示す that ビタミン D made a big difference.
In contrast, earlier 熟考する／考慮するs have shown that lifestyle changes such as diet and 演習 can lower the 半端物s of developing type 2 糖尿病 by 58% over a 類似の period of time, said Dr. Deborah Wexler of the Massachusetts General Hospital 糖尿病 中心 in a 定期刊行物 編集（者）の.
予防の 治療 with the 麻薬 metformin can lower it by 31%, she said.
Volunteers in the D2d 熟考する／考慮する who took ビタミン D had a 類似の 率 of 味方する 影響s as the people who were given placebo pills.
報告（する）／憶測s 解放（する）d in 2016 of two 実験（する）s of ビタミン D as a 糖尿病 予防の, one done in Norway and the other in Japan, also 設立する that type 2 率s were lower with the ビタミン, but the differences were, once again, not 劇の enough to be statistically 重要な.
"Any 利益 of ビタミン D for 糖尿病 予防, if 現在の, is modest and 明確に does not 付随する to a ビタミン D-十分な 全住民," said Dr. Wexler. The question of whether it might help the few people who are ビタミン D deficient remains unanswered.
"The message is there's no 魔法 pill," said Dr. Pittas. "負わせる loss and 増加するing physical activity is still the best way to 妨げる 糖尿病."
The 国家の 学校／設ける of 糖尿病 and Digestive 腎臓 病気s was the 最初の／主要な sponsor of the D2d 熟考する／考慮する.
SOURCE: https://bit .ly/2IoJdD1 and https://bit.ly/2ImibvV The New England 定期刊行物 of 薬／医学, online June 7, 2019
