New £400,000 melanoma ワクチン 先触れ（する）s?start of '癌 renaissance' as UK 裁判，公判s personalised jabs for 肺, bowel, 膵臓 and 肝臓 tumours... but 専門家s 恐れる NHS can't afford them

• e-mail

The UK is entering a '癌 renaissance' with 開拓するing personalised ワクチンs to 戦闘 some of the deadliest tumours 推定する／予想するd by 2030, say 主要な 専門家s.

裁判，公判s are already 進行中で 申し込む／申し出ing 患者s with 肺, 肝臓, 腎臓, bowel and 膵臓 癌 jabs that could 妨げる the 病気 returning.

A first-of-its-肉親，親類d 共同 between the NHS and 癌 ワクチン developers, 発表するd last year, will mean that British 患者s will get 優先 接近 to these game-changing 麻薬s.

The bespoke jabs, created using the same 科学（工学）技術 behind the Covid ワクチンs, train the 団体／死体 to 追跡（する） 負かす／撃墜する 癌 独房s, and 妨げる the 病気 from coming 支援する.

However, there are question 示すs over the affordability of the 治療 which cost around £400,000 per 患者, insiders have told MailOnline.?

Steve Young, 52, from Stevenage is of the first 患者s on the melanoma ワクチン 裁判，公判 at University College Hospital London

Steve is 治めるd his first melanoma jab at the University College London Hospital from Nurse Christian Medina

The news comes after an 告示 today that the first personalised ワクチン for melanoma 肌 癌 was 存在 trialled on NHS 患者s.

早期に results 示唆する the jab can 徹底的に 改善する the 生き残り chances of 患者s with the 病気 ? the deadliest form of 肌 癌.

One 患者 who has already received the ワクチン, Steve Young, 52 from Stevenage, 述べるd it as his 'best chance of stopping the 癌 in its 跡をつけるs'.

This is my best hope of stopping the 病気 in its 跡をつけるs

One of the first 患者s on the 裁判，公判 at UCLH is Steve Young, 52, from Stevenage.

His 'bump on the 長，率いる' ― which he thinks he had for around a １０年間 ― turned out to be melanoma.

He said it was a '大規模な shock' to be 診断するd.

One of the first 患者s on the 裁判，公判 at UCLH is Steve Young, 52, from Stevenage. His 'bump on the 長，率いる' ― which he thinks he had for around a １０年間 ― turned out to be melanoma

'I literally spent two weeks just thinking 'this is it',' he said.

'My dad died of emphysema when he was 57 and I 現実に thought 'I'm going to die younger than my dad'.'

Mr Young said when he was told about the 裁判，公判 at UCLH it 'really 誘発する／引き起こすd my geek レーダ'.

He 追加するd: 'It really piqued my 利益／興味.?

'As soon as they について言及するd this mRNA 科学（工学）技術 that was 存在 used to 潜在的に fight 癌, I was just like, 'it sounds fascinating' and I still feel the same. I'm really, really excited.

'This is my best chance at stopping the 癌 in its 跡をつけるs.'

宣伝

Mr Young was 診断するd with melanoma after a bump on his 長，率いる ? which he thinks he had for around a １０年間 ? turned out to be cancerous.

However, 専門家s say that melanoma is just one of many 癌s that could be cured thanks to personalised ワクチンs.

'These ワクチンs could help 癌 患者s across the board,' says Dr Lennard 物陰／風下, a 癌 ワクチン 専門家 at the University of Oxford.

'This is new tech that we didn't have before that could save the lives of 患者s.

'There are already 裁判，公判s 現在進行中の for 長，率いる and neck, bowel, 膵臓, 肺 and 肝臓 癌s, and the number will only 増加する month-by-month, year-by-year.

'It's a whole field of 薬／医学 which has 爆発するd from nowhere. It feels like the UK is entering a renaissance for 癌 治療.'

Professor 物陰／風下 追加するd: '麻薬 製造業者s are all 的ing 2030 as the year to get these ワクチンs out there.'

癌 ワクチンs are designed to 的 明確な／細部 genetic 突然変異s 設立する in the 癌 独房s.

This means that, should the 癌 return, the 免疫の system will 位置／汚点／見つけ出す it すぐに and destroy the 独房s before they have time to spread.

To create the jab, a 見本 of tumour is 除去するd during the 患者's 外科.

This is then sent to a 研究室／実験室 where the tumour 遺伝子s are sequenced to identify 確かな proteins created by 癌 独房s, known as neoantigens, that will 誘発する／引き起こす an 免疫の 返答.

These are then used to create an individualised mRNA ワクチン ? the same cutting-辛勝する／優位 科学（工学）技術 used to develop several of the Covid jabs.

The ワクチン tells the 患者's 団体／死体 to 生成する the tumour-明確な／細部 neoantigens which in turn train the 免疫の system to recognise and attack the tumour 独房s.?

Data published last year 設立する that, in a small 熟考する／考慮する, high-危険 melanoma 患者s who were given the new jab と一緒に another 免疫の-上げるing 麻薬 were almost half as likely to die or have their 癌 come 支援する after three years, compared to those only taking the immunotherapy.

患者s have to get a new jab, と一緒に a course of immunotherapy, every three weeks for a year.

However, 専門家s say they are 特に excited about the 可能性のある of the ワクチンs to help cure 患者s with 膵臓 癌?? a deadly form of the 病気 with few 効果的な 治療s.

Every year, around 10,000 患者s are 診断するd with 膵臓 癌 ? and around the same die of it 毎年.

The 条件 is so deadly because it is often 診断するd late 予定 to a 欠如（する） of obvious symptoms.

Only around five per cent of 患者s will 生き残る the 病気 for more than a １０年間.

Earlier this month, new data from a 熟考する／考慮する giving mRNA ワクチンs to 膵臓 患者s after 外科 showed 調印するs that it induced a strong 免疫の 返答 that would 減ずる the 危険 of the 病気 returning.

A larger 熟考する／考慮する, 伴う／関わるing 260 患者s, is now 進行中で.

'We've come a long way in the 治療 of melanoma over the years now and we can cure around half of all 患者s,' says Professor Tom Powles, director of Barts' 癌 Centre.

'But there is just nothing that 作品 for 膵臓 癌.

'If given to 患者s 早期に enough, 癌 ワクチンs could open a new 一時期／支部 for 膵臓 患者s by 減ずるing the 危険 of the 病気 returning.

'If I was a 膵臓 癌 患者 this is the 裁判，公判 I would want to get on.'

However, there are 関心s over the cost of the ワクチン.

'現在／一般に, it costs around 500,000 dollars [£399,000] to develop each course of jabs,' says an 産業 source.

The jabs use the same mRNA-based 科学（工学）技術 設立する in the Covid ワクチン to harness the 団体／死体's 免疫の system and kill 癌

'At that price the NHS will struggle to afford them.

'The 麻薬 companies will need to find a way to make the ワクチンs commercially viable.'

But 専門家s say the NHS's 共同 with ワクチン developers Moderna and BioNTech, which will see thousands of UK 患者s 入会させるd on their 裁判，公判s, could 許す Britons to 接近 these new 治療s sooner than those in other countries.

'In the coming years, NHS 癌 患者s can 推定する／予想する to see more 適切な時期s to get の上に these ワクチン 裁判，公判s,' says Dr 物陰／風下.

'These are 適切な時期s 患者s どこかよそで might not get.'