New AI creates 分子s not 設立する in nature that can CHANGE human 遺伝子s to cure even the rarest of 病気s

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AI is used to compose music, 示唆するs recipes and make 投資 決定／判定勝ち（する）s, but a company has designed a system that can edit human 遺伝子s.

California-based?Profluent Bio developed a system 有能な of creating a 範囲 of bespoke cures for 病気 by developing?分子s that have never 存在するd in nature.

DailyMail.com spoke to Ali Madani, CEO of Profluent Bio, who said the AI-made 遺伝子 editors have been 実験（する）d in human 独房s, which 論証するd?high levels of functionality while not editing unintended 場所／位置s in the デオキシリボ核酸.

The AI was trained on a database of 5.1 million?CRISPR-associated (Cas) proteins, 許すing it to create 可能性のある 分子s that could be used in 遺伝子 editing.

The system then 狭くするd 負かす／撃墜する the results to four million sequences, 許すing it to identify the 遺伝子 editor the team 指名するd OpenCRISPR-1.?

実験s showed?OpenCRISPR-1 成し遂げるd 同様に as Cas proteins, but it also?減ずるd the 衝撃 on off-的 場所／位置s by 95 パーセント.

California-based Profluent Bio developed a system 有能な of creating a 範囲 of bespoke cures for 病気 by developing 分子s that have never 存在するd in nature.

The AI was trained on a database of 5.1 million CRISPR-associated (Cas) proteins, 許すing it to create 可能性のある 分子s that could be used in 遺伝子 editing

‘試みる／企てるing to edit human デオキシリボ核酸 with an AI-designed 生物学の system was a 科学の moonshot,'?Madani said.

‘The 分子s do not 存在する in nature like previous 科学（工学）技術s in 遺伝子 editing such as CRISPR.’

CRISPR is a Nobel Prize-winning tec hnique that can be used to edit the genomes of living organisms, cutting a 独房’s 遺伝子s or 追加するing new ones - but it has 以前 relied on ‘遺伝子 editors’? 設立する in bacteria.

The technique has altered 遺伝子s that 原因（となる）?hereditary 条件s, such as sickle 独房 anemia and blindness.

Hilary Eaton, 長，指導者 商売／仕事 Officer at Profluent, said: 'It’s phenomenal that the first CRISPR-based 治療s for genetic 病気s such as sickle 独房 病気 are already changing the lives of 患者s, but there remains an 緊急の need to 加速する the 開発 of this 科学（工学）技術 for thousands of other 現在／一般に incurable 病気s.'

'Our 意向 with OpenCRISPR is to partner with cutting-辛勝する／優位 研究 会・原則s and 麻薬 developers with a powerful and practical way to 安全に 促進する the 開発 of new CRISPR genetic therapies.'

READ MORE:??Humans could be ‘遺伝子 edited’ to 直す／買収する，八百長をする デオキシリボ核酸 problems behind illnesses

?Scientists at Harvard University say they have made a 'base editor' ― or enzymes ― that can 削減（する） out and 取って代わる 欠陥のある 遺伝子s.

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To 達成する the 打開, Madani’s team ‘trained’ Large Language Models on 抱擁する 量s of genetic data - in the same way that ChatGPT is ‘trained’ on text and images from the internet.

‘AI was at the heart of this 業績／成就. We trained large language models (LLMs) on 大規模な 規模 evolutionary sequences and 生物学の 状況,'?Madani said.

‘Our 見通し is to move biology from 存在 constrained by what can be 達成するd in nature to 存在 able to use AI to design new 薬／医学s 正確に によれば our needs.’

The company believes that AI can work as an ‘interpreter to decode the language of life.’

臨床の 裁判，公判s have already 実験（する）d CRISPR 科学（工学）技術 to 扱う／治療する human genetic 病気s - and Madani hopes that the new AI-designed 分子s will 上げる the 能力 of 遺伝子-editing 科学（工学）技術 even その上の.

‘By 首尾よく doing so, we believe we’ve helped to take an important step 今後 に向かって a 未来 where AI can be used to design bespoke 治療s and cures for 患者s in need,' said?Madani.

‘Our 焦点（を合わせる） is on partnering with cutting-辛勝する／優位 研究 会・原則s and 麻薬 developers across the globe to 利用する our OpenCRISPR 遺伝子 editor as a 道具 for 前進するing new and 約束ing 薬／医学s.’

その上の 研究 ‘in other 独房 lines, animals, or 患者s’ is needed to fully 査定する／（税金などを）課す the 業績／成果 of the AI-designed 遺伝子 editors.

Profluent Bio 目的（とする）s to open source its system?for 研究 and 商業の use.

Madani? believes that by ‘open-sourcing’ (where 道具s or code are made 自由に 利用できる for other 研究員s to use) the AI-designed 分子s, he can 抑えるのをやめる その上の creativity in the field.

California-based Profluent Bio developed a system 有能な of creating a 範囲 of bespoke cures for 病気 by developing 分子s that have never 存在するd in nature?

Open sourcing is 一般的に used in ソフトウェア 開発, いっそう少なく so in genetic 研究.

He said, ‘Our goal in open-sourcing OpenCRISPR-1 is to encourage the use of AI for 倫理的な 研究 and 商業の use, 特に in the 開発 of 薬／医学s てこ入れ／借入資本ing CRISPR, the groundbreaking 科学の 発見 that is 存在 used in the 開発 of new 治療s for countless 病気s.

‘We believe by doing so, we can help 加速する the pace of 発見 and 革新 in the field.

As part of this 成果／努力, we’ll be 集会 feedback from the 遺伝子 editing community and using that input to その上の optimize AI-designed 遺伝子 editors.’