Florida イルカ dies of '突然変異するd' bird flu that is 18 TIMES more 抵抗力のある to 麻薬 治療

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A bottlenose イルカ in Florida has become one of the 最新の 哺乳動物s to die from bird flu, によれば a new 報告（する）／憶測.

Scientists from the University of Florida 設立する this particular bird flu?犠牲者 after they were 通知するd of a イルカ that appeared to be in 苦しめる, but a necropsy に引き続いて its death 明らかにする／漏らすd it 契約d a 高度に deadly 緊張する.

The team discovered the ウイルス in the 哺乳動物's brain and 肺s, which had 突然変異するd to become 18 times more 抵抗力のある to 現在の 麻薬 治療s.?

Farmed poultry and wild birds in the US have been 落ちるing 犠牲者 to 高度に pathogenic avian influenza ウイルスs since the end of 2021, but recently it has begun 流出／こぼすing over into cows and other 哺乳動物s.

The イルカ was 報告（する）／憶測d by Florida Fish and 野性生物 公式の／役人s, who spotted the animal stuck between a ドッキングする／減らす／ドックに入れる and a sea 塀で囲む. By the time a 救助（する） team got there, the young animal had died.

This 地図／計画する shows how bird flu has appeared in growing numbers of 哺乳動物s, which some 専門家s say could mean it is 辛勝する／優位ing closer to human spillover in the US

READ MORE: Eighteen 明言する／公表するs 検疫 cows to 停止（させる） bird flu spread

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専門家s 恐れる that 感染s in cattle and other 哺乳動物s could raise the 危険 of the ウイルス adapting to spread in humans.

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As 研究員s 成し遂げるd their necropsy of the イルカ, they identified inflammation in and around its brain and spinal cord.

After the イルカ had 実験（する）d 消極的な for other 感染s that can 原因（となる） this 肉親，親類d of inflammation, they 設立する bird flu antigen and リボ核酸 in its brain and 肺s?

特に, the イルカ was 感染させるd with 高度に pathogenic avian influenza A (H5N1) ウイルス of HA 覆う？ 2.3.4.4b.?

They 設立する some 証拠 of the ウイルス in the 肺s, but most of it was in the brain and the tissue that covers the brain and spinal cord.?

This group of bird flus, called 2.3.4.4b A(H5N1), has been 非難するd for 殺人，大当り sea lions in Peru and Chile, 同様に as harbor and gray 調印（する）s in New England and Canada.

Though it's not 正確に／まさに ありふれた for bird flu to kill 調印（する）s and sea lions, it is not considered rare.

For cetaceans (the group 含むing イルカs and 鯨s), however, bird flu is rare.

There has been a 最近の spread of?2.3.4.4b A(H5N1) の中で cetaceans, wrote the 報告（する）／憶測 authors.

Scientists 設立する 証拠 of influenza A (H5N1) in the dead bottlenose イルカ: (a) viral antigens in the central nervous system; (b) viral リボ核酸 in the same section of the central nervous system; (c) ウイルス antigen in the actual neurons; (d) viral リボ核酸 in the same neurons; (e) traces of ウイルス in the 肺s; and (f) 消極的な 審査する for viral リボ核酸 in the 肺s

It's not （疑いを）晴らす how the bottlenose イルカ in Florida got 感染させるd with bird flu. 感染s in other 海洋 哺乳動物s like 調印（する）s and sea lions is somewhat ありふれた, but it's not ありふれた in イルカs and 鯨s.

It's been 設立する in ありふれた イルカs in Peru, むちの跡s, and England, two harbor porpoises in Sweden and England, and an 大西洋 white-味方するd イルカ in Canada.?

These 事例／患者s have been few and far between, so t's 不明瞭な 正確に／まさに how the bottlenose イルカ got 感染させるd in the Florida 事例／患者.

の直前に the Florida イルカ died, there had been a bird die-off in the area that 専門家s linked to HPAI.

However, genetic 実験（する）ing showed that the flu 原因（となる）ing 地元の bird 突発／発生s did not 株 the exact genetics with the one that killed the イルカ.

Genetic 実験（する）ing 決定するd that the ウイルス had not undergone any 突然変異s that would make it more likely to spread to and 感染させる other 哺乳動物s.

研究員s did find, however, that this イルカ's particular H5N1 緊張する had genetic changes that made it 18 times more 抵抗力のある to one of the antiviral 麻薬s used to 扱う／治療する bird flu.

Scientists 設立する (a) brain hemorrhaging, (b) dead neurons and glial 独房s in the brain, (c) hemorrhaging in the lining of the brain and spinal cord, and (d) 極小の changes to 肺 tissue.

The イルカ in question was first spotted at the end of March 2022, but the 事例／患者 報告（する）／憶測, published in the 定期刊行物 Communications Biology,?did not appear until this month.?

The team's 報告（する）／憶測 示すs the first known instance of influenza A in a ありふれた bottlenos e イルカ, 追加するing to the 団体／死体 of 証拠 that the ウイルス is spreading の中で 哺乳動物s.

Two weeks ago, 18 US 明言する／公表するs 検疫d cattle after 報告（する）／憶測s of bird flu の中で the animals.

And in New York, 多重の wild bird 種類 have 実験（する）d 肯定的な for H5N1?特に.?

It seems that イルカs and 鯨s get 感染させるd 異なって than other animals, with the ウイルス 影響する／感情ing their brain more than their respiratory system like the 肺s and bronchioles.?

'全体にわたる, more 研究 is needed to 決定する the true susceptibility and 大勝する of （危険などに）さらす of influenza ウイルスs in cetaceans,' wrote the scientists behind the new 熟考する／考慮する.

It's possible, they 結論するd, that some 事例／患者s have been 行方不明になるd because of the unique way the 感染 shows up in these animals:?

'Since cetaceans were 以前 thought to have low susceptibility to influenza viral 感染s, this 熟考する／考慮する 強調するs the importance of routinely 実験（する）ing for [高度に pathogenic avian influenza] ウイルスs in all 哺乳動物s and 得るing proper 見本s, 含むing brain, during 検視s.'